Tuesday, October 31, 2017

How do sarms work

SARMS are therapeutic compounds that have anabolic effect with low androgenic properties. They have great androgen receptor specificity, tissue selectivity and they lack steroid like side effects making them the best choice. SARMs provide therapeutic opportunities which include treatment of wounds after burns, cancer, or end-stage renal disease, osteoporosis, frailty, and hypogonadism. They stimulate androgen receptors in muscles and bones.They bind to your cells' androgen receptors. They work through androgen action on skeletal muscles and the bone progenitor cells causing increased cell division and cell hypertrophy where the signals and compounds involved in muscle and bone growth are activated and bone without effect on other body tissues. They cause increased alkaline phosphatase activity and androgen receptor (AR) transcriptional activity in muscle and osteoblastic cell lines in the same manner as the natural androgen ligand dihydrotestosterone (DHT) causing bone and muscle hypertrophy.

SARMS have little effects on the liver and blood pressure. This eliminates the need for preloading and on-cycle support supplements. They also have lower estrogen related side effects and water retention capabilities. They have similar effects to testosterone and have no need for conversion to Estrogen or Dihydrotestosterone. Also they are all taken orally hence no injectables needed. Other benefits include improved strength, anabolic even at low doses, joint healing abilities fat loss, improved libido and sexual function, increased wellbeing and overall well being.

Types of SARMS include Ostarine MK-2866, LGD-4033, Enobosarm, BMS-564, 929, RAD 140, Andarine, YK-11, Acetothiolutamide, S-40503 and JNJ-28330835. The SARMS side effects especially when taken at high doses include acne, baldness, excess body hair growth, gynecomastia, high blood pressure, liver toxicity, suppression of natural testosterone and blurred vision. These side effects are experienced when high doses are used and when the drugs are used for long period hence moderate and short-term users experience few side effects.

References:
IllicitDrugsResearch - http://www.illicitdrugsresearch.eu/2017/01/22/sarms/
livertox - https://livertox.nih.gov/
Heart Healthy Diet - http://www.mayoclinic.org/diseases-conditions/heart-disease/in-depth/heart-healthy-diet/art-20047702

Wednesday, September 17, 2014

Winstrol Fat Loss - Benefits Of Stanozolol Tablets

http://www.iroids.com/winstroll
One of the most popular anabolic steroids for losing bodyfat and weight, Winstrol or Stanozolol is a derivative of Dihydrotestosterone. This anabolic steroid is commonly made a part of cutting cycles by athletes and bodybuilders to gain top shape and lose stubborn belly fat.

Winstrol Fat Loss-Benefits Of Stanozolol Tablets

Classified as a controlled substance under the Anabolic Steroids Control Act of 1990 and assigned to Schedule III, Winstrol has the molecular weight of 344.5392 g/mol at the base. The chemical name of Stanozolol is 17-methyl-2' H -5(alpha)-androst-2-eno [3,2- c  ]pyrazol-17(beta)-ol and the anabolic-androgenic ratio of this steroid compound is 320:30 and it has the molecular formula of C22H36N2O.

One of the biggest benefits of Winstrol lies in the fact that this drug can facilitate expect a dry look to physique if the body fat is relatively low. Secondly, Winstrol can dramatically stimulate nitrogen retention and protein synthesis to a significant extent while strengthening tendons and ligaments. Thirdly, this weight loss drug can temporarily prevent steroid hormones from exerting their activities, primarily because of its plasma-binding characteristics as it has a dramatic effect on sex hormone-binding globulin levels in the body.

Winstrol Fat Loss-Benefits Of Stanozolol Tablets

Furthermore, Winstrol can improve percentage of free testosterone circulating in the body that may further enhance the potency of concurrently used anabolic steroids. Popular with women and beginners as with experienced male athletes, Winstrol is admired worldwide for its anabolic nature and very few androgenic side effects.

However, Winstrol abuse or overdosing can lead to health complications such as elevated liver values, liver toxicity, negative effects on cholesterol levels, acne, prostate enlargement, aggravation of male pattern baldness, deepening of the voice, body/facial hair growth, and enlargement of the clitoris. Abuse of Winstrol may even cause inhibition of testicularfunction, testicular atrophy and oligospermia, impotence, chronic priapism, epididymitis and bladder irritability, edema, retention of serum electrolytes (sodium, chloride, potassium, phosphate, and calcium).

Friday, September 12, 2014

Winstrol Weight Loss Cycles - Stanozolol For Elite Athletes


One of the most popular fat loss drugs in the world of bodybuilding, Winstrol or Stanozolol is a safe yet highly effective fat loss drug. Commonly incorporated by athletes in cutting cycles, this weight loss drug has the ability of dramatically reducing abdominal and visceral fat levels while helping athletes add on to muscle strength and physical appearance. This drug is also beneficial to stimulate immediate-early gene expression in a manner that is independent of the androgen receptor.

Winstrol Weight Loss Cycles-Stanozolol For Elite Athletes

Winstrol demonstrates unmatched great efficacy in allowing the body to utilize more amounts of Testosterone to burn excess fat tissues. This weight loss drug also has the ability to stimulate the production of prostaglandin E2 and the matrix metalloproteases collegenase and stromelysin in skin fibroblasts. Moreover, this fat loss drug can be associated with the inhibition of growth factor stimulated DNA synthesis and fibroblasts.


Week
Clenbuterol
Winstrol
Proviron
Salbutol
1
60 mcg per day
50 mg per day

16 mg per day
2

50 mg per day
25 mg per day
16 mg per day
3
80 mcg per day
50 mg per day
25 mg per day
16 mg per day
4

50 mg per day
25 mg per day

5
60 mcg per day
50 mg per day
25 mg per day
16 mg per day
6

50 mg per day
25 mg per day


Week
Testosterone enanthate
Equipoise
Winstrol
1
450 mg per week
450 mg per week
50 mg per day
2
450 mg per week
450 mg per week
50 mg per day
3
450 mg per week
450 mg per week
50 mg per day
4
450 mg per week
450 mg per week
50 mg per day
5
450 mg per week
450 mg per week
50 mg per day
6
450 mg per week
450 mg per week
50 mg per day
7
450 mg per week
450 mg per week
50 mg per day
8
450 mg per week
450 mg per week

9
450 mg per week
450 mg per week

10
450 mg per week
450 mg per week

11
450 mg per week
450 mg per week

12
450 mg per week
450 mg per week


Winstrol Weight Loss Cycles-Stanozolol For Elite Athletes

Week
Winstrol
Anavar
Arimidex
1
40 mg every day
40 mg every day

2
50 mg every day
50 mg every day

3
50 mg every day
70 mg every day

4
70 mg every day
90 mg every day

5
70 mg every day
90 mg every day

6
80 mg every day
80 mg every day

7
50 mg every day
100 mg every day

8
50 mg every day
100 mg every day

9


1 mg every day
10


1 mg every day
11


1 mg every day
12


1 mg every day

Winstrol is usually stacked with anabolic androgenic steroids such as Equipoise, Deca Durabolin, or Primobolan. It may be stacked with Testosterone, Dianabol, or Anadrol for a bulking cycle and with Trenbolone or Halotestin during a dieting phase.

Winstrol abuse may lead to health complications such as oligospermia, chronic priapism, epididymitis, bladder irritability, and edema. Overdosing of this fat loss drug can result in inhibition of testicular function, testicular atrophy, increased or decreased libido, habituation, excitation, insomnia, depression, nausea, vomiting, and diarrhea.


Saturday, September 6, 2014

Winstrol Fat Loss Cycles - Stanozolol Cutting Cycles

Winstrol Fat Loss Cycles- Stanozolol Cutting Cycles

Winstrol or Stanozolol is a synthetic anabolic steroid derived from Dihydrotestosterone. This performance enhancing drug is used to improve physical appearance and get in top shape. Winstrol is also known to reduce abdominal and visceral fat. Classified as a controlled substance under the Anabolic Steroids Control Act of 1990 and assigned to Schedule III, this drug is medically recommended for treating severe health complications such as anemia and hereditary angioedema.


During cutting cycles, Winstrol is used along with other steroids such as Clenbuterol and derivatives of Testosterone (testosterone enanthate or propionate) for preserving lean body mass while metabolizing adipose. This drug is also admired for its ability to improve water excretion in the body. Winstrol has a positive and synergetic effect with other anabolic steroids used in an anabolic steroid cycle. Moreover, Winstrol can be useful for improving body strength, without causing an increase in the level of body weight.


Week
Clenbuterol
Winstrol
Proviron
Salbutol
1
80 mcg per day
50 mg per day

16 mg per day
2

50 mg per day
25 mg per day
16 mg per day
3
80 mcg per day
60 mg per day
25 mg per day
16 mg per day
4

60 mg per day
25 mg per day

5
80 mcg per day
50 mg per day
25 mg per day
16 mg per day
6

50 mg per day
25 mg per day


Week
Testosterone enanthate
Equipoise
Winstrol
1
500 mg per week
400 mg per week
50 mg per day
2
500 mg per week
400 mg per week
50 mg per day
3
500 mg per week
400 mg per week
50 mg per day
4
500 mg per week
500 mg per week
50 mg per day
5
500 mg per week
500 mg per week
50 mg per day
6
500 mg per week
500 mg per week
50 mg per day
7
500 mg per week
500 mg per week
50 mg per day
8
500 mg per week
500 mg per week

9
500 mg per week
600 mg per week

10
500 mg per week
600 mg per week

11
500 mg per week
500 mg per week

12
500 mg per week
500 mg per week


Winstrol Fat Loss Cycles- Stanozolol Cutting Cycles


Week
Winstrol
Anavar
Arimidex
1
40 mg every day
40 mg every day

2
50 mg every day
50 mg every day

3
60 mg every day
70 mg every day

4
70 mg every day
90 mg every day

5
70 mg every day
90 mg every day

6
80 mg every day
80 mg every day

7
50 mg every day
100 mg every day

8
50 mg every day
100 mg every day

9


1 mg every day
10


1 mg every day
11


1 mg every day
12


1 mg every day


Sideeffects of Winstrol may include health complications like impotence, chronic priapism, epididymitis, inhibition of testicular function, testicular atrophy and oligospermia, or bladder irritability. Winstrol abuse can result in edema or retention of serum electrolytes (sodium, chloride, potassium, phosphate, and calcium). It is important to note that Winstrol is contraindicated to people who are diagnosed with health conditions like testicular atrophy, breast cancer, liver damage, kidney damage, stroke, high blood pressure, and respiratory problems.